Posts Tagged: ‘pharmaceuticals’

For those of us living in the United States, we know that our health care system is broken. We know it is broken in a thousand different ways. This is a recent and most telling example: Premature labor drug spikes from $10 to $1,500 Whether that price spike is caused by pure, unregulated money-grubbing greed, [...]

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There is this curious aspect of medical science called the placebo effect and it gets largely ignored, in part because we simply don’t understand it and also because it undermines a lot of science. As it looks from the outside, the placebo effect appears to be evidence that the mind can trick the body into healing itself. The term is interchangeable with the power of suggestion, magic, the Dodo Bird Effect (in psychology) and “What in the name of God is going on?!”

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One of the most vitally important parts of any prescription drug regimen for treating depression is that the prescription drug actually work. Becasue of this maxim, clinically depressed patients who are taking the drug reboxetine are going to have trouble getting to well.

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Have you ever heard of glucosamine and chondroitin? Chances are you have, in the form of thousands of radio and TV ads. These ads claim that glucosamine and chondroitin will reduce joint pain. The only problem is that they do not have that effect at all…

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(Click here to read part one.)

Certainly, the hard sciences have their massive failures. Eugenics, cloud seeding and String Theory come to mind. We are in that bleak period in our understanding of the universe between the moment we have all of the pieces to the puzzle laid out before us and the time we figure out how they all fit together. (Things will likely become exponentially bleaker once the puzzle is complete, though, I’m betting.)

Neuroscience and genetics are great examples. We have in out hands the functional MRI, which allows us to observe the brain as it functions, and a map of the human genome. Both are among the most potent scientific triumphs, yet we haven’t fully learned how to properly use them. Our cleverness in creating technology has exceeded our ability to use them to their fullest capacity. This understanding will surely catch up to the technology in the near future; the point is that with hard disciplines that use the scientific method like neuroscience and genetics, at least we can replicate the failures along the way.

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The Guardian’s science writer, Ben Goldacre, who also runs the Bad Science blog across the pond, recently posted about a disgraced anesthesiologist from Massachusetts named Dr. Scott S. Rueben. Few things evoke Goldacre’s vitriol more than fraudulent scientists — his post on Reuben is titled “Scumbag.”

The Wall Street Journal reports that between 1996 and 2008 Reuben published 21 medical studies on pharmaceutical painkillers, including Vioxx and Celebrex. Dr. Reuben was, until very recently, the chief of acute pain at Baystate Medical Center in Springfield, so when he published his studies, people listened. The problem is that Reuben allegedly made up much of the data he cited in the studies to suit his conclusions.

Precisely why he would have done this appears to have been a matter of money. A financial link between Reuben and Pfizer, maker of Bextra, on which Reuben published favorable studies, has been found.

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